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KMID : 0363219710090030071
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Korean Journal of Dermatology
1971 Volume.9 No. 3 p.71 ~ p.75
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One Case of Poikilodermatomyositis
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朴允基/Park, Yoon Kee
朴旭和/禹泰河/Bark, Wook Hwa/Woo, Tae Ha
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Abstract
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The authers observed one case of typical poikilodermatomyositis who was 47 year old female.
The poikilodermatomyositis is a rare disease which is a variant of dermatomyositis and has never been reported in Korea.
This patient complained of a weakness of left. lower leg and tingling sensation of both fingers since one year ago. And she has a difficulty of both finger flexion since 20 days ago.
The skin lesions revealed mottled dark brownish pigmentation, hardness, scattered atrophic patches and telangiectasia in the lesion on the left lower leg since one year ago. The same skin changes appeared on the thigh, lower abdomen and upper chest on 4 months ago.
Histopathologically, a biopsy was performed from the skin of lower leg, the skin shows typical poikiloderma, i.e. the epidermis shows moderate atrophy of the stratum malpighii, flattened rete ridges and hydropic degeneration of the basal cells. The dermis is edematous and a band like dense lymphocytic cellular infiltration. And the muscle biopsy from gastrocnemius muscle shows dermatomyositis finding which the muscle bundles are edematous and degenerative. Many inflammatory cells present between muscle bundles but there is no suppurative change.
Diagnosis was confirmed by clinical appearance, histopathologically and other laboratory studies.
The patient was markedly improved by the prednisolone 80 mg and vasculat (vascular dilatator) 100 mg daily.
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